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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

Open Access publications hosted on VTechWorks
In-House Research
<p>Regioselective and controlled-density branching in amylose esters</p>

Regioselective and controlled-density branching in amylose esters

Jeffrey E. Thompson a, Kevin J. Edgar a b

a Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA 24061, Unit...

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In-House Research
<p>Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis</p>

Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis

Yuefan Song a, Amit Singh b, Maisha M. Feroz a c, Shirley Xu a c, Fuming Zhang a...

a Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>Chlorination of hydroxyethyl cellulose enables selective functionalization</p>

Chlorination of hydroxyethyl cellulose enables selective functionalization

Chengzhe Gao, Stella P. Petrova, and Kevin J. Edgar

C. Gao · S. P. Petrova  Department of Chemistry, Virginia Tech, Blacksburg, VA 2...

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In-House Research
<p>Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms</p>

Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms

Laura De los Santos 1, Robert L. Beckman IV 1, Christina DeBarro 1, James E. Kee...

1 Division of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, ...

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In-House Research
<p>Probing the Role of Protein Conformational Changes in the Mechanism of Prenylated-FMN-dependent Phenazine-1-carboxylic Acid Decarboxylase</p>

Probing the Role of Protein Conformational Changes in the Mechanism of Prenylated-FMN-dependent Phenazine-1-carboxylic Acid Decarboxylase

Prathamesh M. Datar 1, Soumil Y. Joshi 2, Sanket A. Deshmukh 2, E. Neil G. Marsh...

1 Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA

2...

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In-House Research
<p>Heparin Specifically Inhibits CRISPR/Cas12 Activation, Enabling Ultrasensitive Heparin Detection and Gene Editing Regulation</p>

Heparin Specifically Inhibits CRISPR/Cas12 Activation, Enabling Ultrasensitive Heparin Detection and Gene Editing Regulation

Min Cao, Xinlan Bian, Zhirun Ji, Muhammad Sohail, Fuming Zhang, Robert J. Linhar...

Min Cao − School of Food Science and PharmaceuticalEngineering, Nanjing Normal U...

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In-House Research
<p>Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway</p>

Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway

Wenjing Zhang a 1, Nan Wu a 1, Hong Wang a, Genxiang Mao c, Xiaojun Yan d, Fumin...

aDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang...

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In-House Research
<p>Fibrolamellar Carcinomas&ndash;Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides</p>

Fibrolamellar Carcinomas–Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides

Wencheng Zhang a b c d 1, Yongmei Xu e f 1 2, Xicheng Wang b c d 3, Tsunekazu Oi...

aDepartment of Cell Biology and Physiology, University of North Carolina, Chapel...

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In-House Research
<p>Improving biosensor accuracy and speed using dynamic signal change and theory-guided deep learning</p>

Improving biosensor accuracy and speed using dynamic signal change and theory-guided deep learning

Junru Zhang a, Purna Srivatsa b, Fazel Haq Ahmadzai a, Yang Liu a c, Xuerui Song...

aGrado Department of Industrial and Systems Engineering, Virginia Tech, Blacksbu...

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In-House Research
<p>Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones</p>

Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones

Stancanelli, Eduardo; Liu, Wei; Su, Guowei; Padagala, Vijay; Liu, Jian

  • 1Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pha...
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In-House Research
<p>A review of recent advances and applications of machine learning in tribology</p>

A review of recent advances and applications of machine learning in tribology

Sose, Abhishek T; Joshi, Soumil Y; Kunche, Lakshmi Kumar; Wang, Fangxi; Deshmukh...

Department of Chemical Engineering, Virginia Tech, Blacksburg, VA 24061, USA

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In-House Research
<p>Absolute pharmacokinetics of heparin in primates</p>

Absolute pharmacokinetics of heparin in primates

Yuefan Song a, Ahmed Kouta b, Lee M. Cera c, Ke Xia a, Fuming Zhang a, Roland Kr...

aCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic ...

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In-House Research
<p>Data Driven Discovery of MOFs for Hydrogen Gas Adsorption</p>

Data Driven Discovery of MOFs for Hydrogen Gas Adsorption

Singh, Samrendra K.; Sose, Abhishek T.; Wang, Fangxi; Bejagam, Karteek K.; Deshm...

Department of Chemical Engineering, Virginia Tech, Blacksburg, Virginia 24061, U...

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In-House Research
<p>Data Driven Computational Design and Experimental Validation of Drugs for Accelerated Mitigation of Pandemic-like Scenarios</p>

Data Driven Computational Design and Experimental Validation of Drugs for Accelerated Mitigation of Pandemic-like Scenarios

Singh, Samrendra K.; King, Kelsie; Gannett, Cole; Chuong, Christina; Joshi, Soum...

Department of Chemical Engineering, Virginia Tech, Blacksburg, Virginia 24061, U...

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In-House Research
<p>New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry</p>

New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry

Deling Shi 1 2, Huimin Zhao 1, Changkai Bu 1, Keith Fraser 2 3, Haoran Wang 1, J...

1National Glycoengineering Research Center, Shandong University, Qingdao, Shando...

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In-House Research
<p>Ring-opening metathesis polymerization of norbornene&ndash;benzoladderene (macro)monomers</p>

Ring-opening metathesis polymerization of norbornene–benzoladderene (macro)monomers

aDepartment of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA

bMacromole...

Samantha J. Scannelli,ab   Mohammed Alaboalirat,ab   Diego Troya  ab  and  John ...

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In-House Research
<p>Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation</p>

Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation

Mahbuba, Deena Al; Masuko, Sayaka; Wang, Shiwei; Syangtan, Deepsing; Kang, Jeong...

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts...

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External User
<p>Systematic Evaluation of Macromolecular Carbohydrate-LectinRecognition Using Precision Glycopolymers</p>

Systematic Evaluation of Macromolecular Carbohydrate-LectinRecognition Using Precision Glycopolymers

Cole A. Williams*, Daniel J. Stone*, Soumil Y. Joshi, Gokhan Yilmaz, Parisa Farz...

Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712,...

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In-House Research
<p>Position-specific&nbsp;<em>N</em>- and&nbsp;<em>O</em>-glycosylation of the reactive center loop impacts neutrophil elastase&ndash;mediated proteolysis of corticosteroid-binding globulin</p>

Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase–mediated proteolysis of corticosteroid-binding globulin

Anastasia Chernykh 1, Jodie L. Abrahams 1 2, Oliver C. Grant 3, Lucas Kambanis 4...

School of Natural Sciences, Macquarie University, Sydney, New South Wales, Austr...

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In-House Research
<p>Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin</p>

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

J. Yang; Y. Song; W. Jin; K. Xia; G. C. Burnett; W. Qiao; J. T. Bates; V. H. Pom...

1The Key Laboratory of Molecular Microbiology and Technology, Ministry of Educat...

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