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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

Open Access publications hosted on VTechWorks
In-House Research
<p>Toward Automatic Inference of Glycan Linkages Using MSn and Machine Learning - Proof of Concept Using Sialic Acid Linkages</p>

Toward Automatic Inference of Glycan Linkages Using MSn and Machine Learning - Proof of Concept Using Sialic Acid Linkages

Xinyi Ni, Nathan B. Murray, Stephanie Archer-Hartmann, Lauren E. Pepi, Richard F...

  1. Brandeis University
  2. University of Georgia, Athens
  3. Virginia Tech
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In-House Research
<p>Fibrolamellar Carcinomas&ndash;Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides</p>

Fibrolamellar Carcinomas–Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides

Wencheng Zhang a b c d 1, Yongmei Xu e f 1 2, Xicheng Wang b c d 3, Tsunekazu Oi...

aDepartment of Cell Biology and Physiology, University of North Carolina, Chapel...

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In-House Research
<p>Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2</p>

Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2

Wuo, Michael G.; Dugan, Amanda E.; Halim, Melanie; Hauser, Blake M.; Feldman, Ja...

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massa...

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In-House Research
<p>New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry</p>

New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry

Deling Shi 1 2, Huimin Zhao 1, Changkai Bu 1, Keith Fraser 2 3, Haoran Wang 1, J...

1National Glycoengineering Research Center, Shandong University, Qingdao, Shando...

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In-House Research
<p>Synthesis and real-time characterization of self-healing, injectable, fast-gelling hydrogels based on alginate multi-reducing end polysaccharides (MREPs)</p>

Synthesis and real-time characterization of self-healing, injectable, fast-gelling hydrogels based on alginate multi-reducing end polysaccharides (MREPs)

Zhenghao Zhai a.,Yang Zhou b,Ishani Sarkar e,Yang Liu a,Yimin Yao a c,Junru Zhan...

a. Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA 24061, Uni...

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In-House Research
<p>Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms</p>

Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms

Laura De los Santos 1, Robert L. Beckman IV 1, Christina DeBarro 1, James E. Kee...

1 Division of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, ...

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In-House Research
<p>Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones</p>

Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones

Stancanelli, Eduardo; Liu, Wei; Su, Guowei; Padagala, Vijay; Liu, Jian

  • 1Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pha...
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External User
<p>Are N-linked glycans intrinsically disordered?</p>

Are N-linked glycans intrinsically disordered?

Eliza Gazaway, Rajan Kandel, Oliver C. Grant, Robert J. Woods

Complex Carbohydrate Research Center and Department of Biochemistry and Molecula...

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In-House Research
<p>Activities of Family 18 Chitinases on Amorphous Regenerated Chitin Thin Films and Dissolved Chitin Oligosaccharides: Comparison with Family 19 Chitinases</p>

Activities of Family 18 Chitinases on Amorphous Regenerated Chitin Thin Films and Dissolved Chitin Oligosaccharides: Comparison with Family 19 Chitinases

Yu, Guoqiang; Liu, Gehui; Liu, Tianyi; Fink, Ethan H.; Esker, Alan R.

Department of Chemistry, Virginia Tech, Blacksburg, Virginia24061, United States

...
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In-House Research
<p>Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5</p>

Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

Deling Shi1,2, Changkai Bu1, Peng He2, Yuefan Song2, Jonathan S. Dordick2, Rober...

1National Glycoengineering Research Center, Shandong University, Qingdao 266237,...

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In-House Research
<p>Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants</p>

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Gelbach, Adrianne L., Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Far...

1Department of Biological Sciences, Center for Biotechnology and Interdisciplina...

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In-House Research
<p>Fractionation of sulfated galactan from the red alga&nbsp;<em>Botryocladia occidentalis</em>&nbsp;separates its anticoagulant and anti-SARS-CoV-2 properties</p>

Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties

Seon Beom Kim 1, Mary Zoepfl 2, Priyanka Samanta 1, Fuming Zhang 3, Ke Xia 3, Re...

  1. Department of BioMolecular Sciences, University of Mississippi, University, M...
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In-House Research
<p>Expedient Synthesis of a Library of Heparan Sulfate-Like &ldquo;Head-to-Tail&rdquo; Linked Multimers for Structure and Activity Relationship Studies</p>

Expedient Synthesis of a Library of Heparan Sulfate-Like “Head-to-Tail” Linked Multimers for Structure and Activity Relationship Studies

Dr. Jicheng Zhang, Dr. Li Liang, Dr. Weizhun Yang, Dr. Sherif Ramadan, Dr. Kedar...

Department of Chemistry, Michigan State University, East Lansing, MI 48824 USA

...
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In-House Research
<p>Anti-SARS-CoV-2 and anticoagulant properties of&nbsp;<em>Pentacta pygmaea</em>&nbsp;fucosylated chondroitin sulfate depend on high molecular weight structures</p>

Anti-SARS-CoV-2 and anticoagulant properties of Pentacta pygmaea fucosylated chondroitin sulfate depend on high molecular weight structures

Rohini Dwivedi, Poonam Sharma, Friederike Eilts, Fuming Zhang, Robert J Linhardt...

Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississi...

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In-House Research
<p>A Cluster Sequencing Strategy To Determine the Consensus Affinity Domains in Heparin for Its Binding to Specific Proteins</p>

A Cluster Sequencing Strategy To Determine the Consensus Affinity Domains in Heparin for Its Binding to Specific Proteins

Deling Shi, Anran Sheng, Changkai Bu, Zizhe An, Xueying Cui, Xiaojun Sun, Hongme...

National Glycoengineering Research Center, Shandong University, Qingdao, Shandon...

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In-House Research
<p>Chemoenzymatic Synthesis of Homogeneous Heparan Sulfate and Chondroitin Sulfate Chimeras</p>

Chemoenzymatic Synthesis of Homogeneous Heparan Sulfate and Chondroitin Sulfate Chimeras

Eduardo Stancanelli, Wei Liu, Rylee Wander, Jine Li, Zhangjie Wang, Katelyn Arno...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Structural and Substrate Specificity Analysis of 3-<em>O</em>-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate</p>

Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate

Rylee Wander, Andrea M. Kaminski, Zhangjie Wang, Eduardo Stancanelli, Yongmei Xu...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Investigation of the pharmacokinetic properties of synthetic heparan sulfate oligosaccharides</p>

Investigation of the pharmacokinetic properties of synthetic heparan sulfate oligosaccharides

Katelyn Arnold, Zhangjie Wang, Andrew Lucas, William Zamboni, Yongmei Xu, Jian L...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Increased 3-O-sulfated heparan sulfate in Alzheimer&rsquo;s disease brain is associated with genetic risk gene HS3ST1</p>

Increased 3-O-sulfated heparan sulfate in Alzheimer’s disease brain is associated with genetic risk gene HS3ST1

Zhangjie Wang, Vaishali N. Patel, Xuehong Song, Yongmei Xu, Andrea M. Kaminski, ...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Activities of Family 18 Chitinases on Amorphous Regenerated Chitin Thin Films and Dissolved Chitin Oligosaccharides: Comparison with Family 19 Chitinases</p>

Activities of Family 18 Chitinases on Amorphous Regenerated Chitin Thin Films and Dissolved Chitin Oligosaccharides: Comparison with Family 19 Chitinases

Guoqiang Yu, Gehui Liu, Tianyi Liu, Ethan H. Fink, and Alan R. Esker*

Department of Chemistry, Virginia Tech, Blacksburg, Virginia24061, United States

...

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