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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

Open Access publications hosted on VTechWorks
In-House Research
<p>Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2</p>

Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2

Wuo, Michael G.; Dugan, Amanda E.; Halim, Melanie; Hauser, Blake M.; Feldman, Ja...

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massa...

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In-House Research
<p>Glycoproteomic characterization of Neuropilin-1 reveals critical glycosylation sites for SARS-CoV-2 entry</p>

Glycoproteomic characterization of Neuropilin-1 reveals critical glycosylation sites for SARS-CoV-2 entry

Tuhin Das, Shuhong Luo, Panning Wang, Jianmin Fang, Asif Shajahan, Lauren Peppi,...

RayBiotech Guangzhou Co. Ltd. Guangzhou, Guangzhou 510000, China; RayBiotech Inc...

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In-House Research
<p>Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation</p>

Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

Qi Zhang, Weichun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar Syed, Vija...

1 Laboratory of Molecular Biology, National Institute of Diabetes, Digestive, an...

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In-House Research
<p>Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis</p>

Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis

Yuefan Song a, Amit Singh b, Maisha M. Feroz a c, Shirley Xu a c, Fuming Zhang a...

a Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>Data Driven Computational Design and Experimental Validation of Drugs for Accelerated Mitigation of Pandemic-like Scenarios</p>

Data Driven Computational Design and Experimental Validation of Drugs for Accelerated Mitigation of Pandemic-like Scenarios

Singh, Samrendra K.; King, Kelsie; Gannett, Cole; Chuong, Christina; Joshi, Soum...

Department of Chemical Engineering, Virginia Tech, Blacksburg, Virginia 24061, U...

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External User
<p>Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation</p>

Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation

Savanna Skeeters, Kamal Bagale, Galina Stepanyuk, David Thieker, Aaron Aguhob, K...

Vascular Medicine Institute, School of Medicine, University of Pittsburgh, Pitts...

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External User
<p>Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation</p>

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Li...

Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, U...

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In-House Research
<p>Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5</p>

Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

Deling Shi1,2, Changkai Bu1, Peng He2, Yuefan Song2, Jonathan S. Dordick2, Rober...

1National Glycoengineering Research Center, Shandong University, Qingdao 266237,...

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In-House Research
<p>The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics</p>

The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics

Friederike Eilts a b 1, Sarah Bauer a 1, Keith Fraser c 1, Jonathan S. Dordick a...

aDepartment of Chemical and Biological Engineering, Center for Biotechnology and...

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In-House Research
<p>Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants</p>

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Gelbach, Adrianne L., Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Far...

1Department of Biological Sciences, Center for Biotechnology and Interdisciplina...

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In-House Research
<p>Fractionation of sulfated galactan from the red alga&nbsp;<em>Botryocladia occidentalis</em>&nbsp;separates its anticoagulant and anti-SARS-CoV-2 properties</p>

Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties

Seon Beom Kim 1, Mary Zoepfl 2, Priyanka Samanta 1, Fuming Zhang 3, Ke Xia 3, Re...

  1. Department of BioMolecular Sciences, University of Mississippi, University, M...
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In-House Research
<p>Anti-SARS-CoV-2 and anticoagulant properties of&nbsp;<em>Pentacta pygmaea</em>&nbsp;fucosylated chondroitin sulfate depend on high molecular weight structures</p>

Anti-SARS-CoV-2 and anticoagulant properties of Pentacta pygmaea fucosylated chondroitin sulfate depend on high molecular weight structures

Rohini Dwivedi, Poonam Sharma, Friederike Eilts, Fuming Zhang, Robert J Linhardt...

Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississi...

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In-House Research
<p>Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection</p>

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection

Rohini Dwivedi 1, Priyanka Samanta 1, Poonam Sharma 2, Fuming Zhang 3, Sushil K....

  1. Department of BioMolecular Sciences, University of Mississippi, Oxford, Missi...
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In-House Research
<p>Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate</p>

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate

Fuming Zhang1,*, Peng He2, Andre L. Rodrigues1, Walter Jeske3, Ritesh Tandon4,5,...

  1. Department of Chemical and Biological Engineering, Center for Biotechnology a...
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In-House Research
<p>Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant</p>

Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant

Peng He1,2 · Yuefan Song1,3 · Weihua Jin1,4 · Yunran Li1,3 · Ke Xia1,3 · Seon Be...

1 Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic...

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In-House Research
<p>Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from&nbsp;Monostroma nitidum</p>

Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from Monostroma nitidum

Song, Yuefan, Peng He, Andre L. Rodrigues, Payel Datta, Ritesh Tandon, John T. B...

Departments of Chemistry and Chemical Biology, Center for Biotechnology and Inte...

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In-House Research
<p>The Sea Cucumber Thyonella gemmata Contains a Low Anticoagulant Sulfated Fucan with High Anti-SARS-CoV-2 Actions against Wild-Type and Delta Variants</p>

The Sea Cucumber Thyonella gemmata Contains a Low Anticoagulant Sulfated Fucan with High Anti-SARS-CoV-2 Actions against Wild-Type and Delta Variants

Rohini Dwivedi,  Marwa Farrag, Poonam Sharma, Deling Shi, Anter A. Shami, Sandee...

Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississi...

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In-House Research
<p>Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern</p>

Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern

Asif Shajahan, Lauren E. Pepi, Bhoj Kumar, Nathan B. Murray & Parastoo Azadi

Vaccine Production Program, Vaccine Research Center, National Institutes of Heal...

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External User
<p>Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2</p>

Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV‑2

Michael G. Wuo, Amanda E. Dugan, Melanie Halim, Blake M. Hauser, Jared Feldman, ...

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massa...

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In-House Research
<p>Synthesis of multivalent sialyllactose-conjugated PAMAM dendrimers: Binding to SARS-CoV-2 spike protein and influenza hemagglutinin</p>

Synthesis of multivalent sialyllactose-conjugated PAMAM dendrimers: Binding to SARS-CoV-2 spike protein and influenza hemagglutinin

Peng He a b, Ke Xia a b, Yuefan Song a b, Ritesh Tandon c, Rudra Channappanavar ...

Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute...

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